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Using Systems Biology Based Approaches for Considerations Across the Life Course: Views from Public Health and Preventative Medicine

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Date Developed: 3/29/2018. Source: UCLA Center for Healthier Children, Families & Communities, Maternal and Child Health Life Course Research Network (LCRN). Presenter(s): Elaine Faustman, PhD. Type: Webinar. Level: Introductory. Length: 15 minutes.


This talk focuses on how public health and preventive medical scientists, as well as developmental and reproductive toxicologists, interpret and apply life course health developmental principles, with an emphasis on the first four principles of the Life Course Health Development (LCHD) framework (Health Development, Unfolding, Complexity, and Timing). The focus of this talk is on early development and childhood.

Learning Objectives

1. Identifying how systems biology concepts inform public health decisions for improving health development

2. Defining the life course “exposome” taking lessons from a child cohort study

3. Discussing approaches for improving our understanding of within and between human variability across development using evolutionary biology principles

4. Applying ontologies for linking and translating observations across model systems and biomarkers for informing human population research

5. Understanding how integrating systems biology concepts improves our health surveillance and intervention

This project is supported by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) under grant number UE8MC25742; MCH Navigator for $225,000/year. This information or content and conclusions are those of the author and should not be construed as the official position or policy of, nor should any endorsements be inferred by HRSA, HHS or the U.S. Government.